Detection of blaCTX-M Genes among Extended Spectrum Beta Lactamase producing Pseudomonas aeruginosa isolated from Clinical Specimens in Erbil

Pseudomonas aeruginosa is one of the most common opportunistic pathogens that cause infections. The drug resistance in may relate to production broad spectrum beta lactamase enzymes. This study aimed detect multidrug resistant, extensively resistant and pan isolates determine frequency extended lactamases enzymes by using a reliable test for detection blaCTX-M1, blaCTX-M2 blaCTX-M3 genes aeruginosa. isolated from different clinical samples, including sputum, wound, burn urine. Identification antibiotic susceptibility were made VITEK® 2 automated system. confirmed 16S ribosomal ribonucleic acid. bacterial deoxyribonucleic acid was extracted specific primers used genes. 62 strains obtained 650 specimens (9.54 %). Of isolates, highest resistances related antibiotics ticarcillin, ticarcillin/clavulanic acid, piperacillin, piperacillin/tazobactam, ceftazidime cefepime (100 However, lowest observed meropenem, imipenem (3.23 %), amikacin, ciprofloxacin (6.45 %) gentamycin, tobramycin (19.35 Out 46 (74.19 multidrugresistance strains, extensive drug-resistance no isolated. gene blaCTX-M1 12 5 (8.06 all negative blaCTX-3 gene. highlights increased prevalence blaCTX-M provide with an additional powerful mechanism potentially serious implications, limitation therapeutic options. incidence varies geographic location time.